• Associate Professor Puri and Dr Gupta with the bioreactor. 
Image: Flinders University
    Associate Professor Puri and Dr Gupta with the bioreactor. Image: Flinders University
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Flinders University researchers say a fungus-like microbe from South Australia could prove to be a vital ingredient in making everything from nutritional supplements, medicines and biofuels to animal-free meat.

Flinders University’s College of Medicine and Public Health medical biotechnology researcher and associate professor Munish Puri said that currently the global market for nutritional supplements is increasing in value, with more and more people turning to them for added health and diet benefits.

“However, our current sources of these products – namely animals including sea creatures – are not sustainable in the long run, so there is a need to search for alternative sources of protein and lipids required in their production,” said Puri.

Writing in the journal Trends in Biotechnology, Puri and colleagues say thraustochytrids (a group of marine microbes) could prove a valuable source for not only nutritional supplements, but provide for other industries, to produce medicine, cosmetics, aquaculture, biofuels and, eventually, animal-free meat.

“By tuning the thraustochytrids through precision fermentation, we can produce single-cell oil (SCO), which can be used by the nutraceutical industry for producing supplements and other nutraceuticals, with the added advantage that it doesn’t require agricultural land and can be cultivated in a controlled environment, keeping the SCO free from contamination,” said Puri.

“We also know that thraustochytrids can produce a wide range of high-value bioproducts, such as omega-3 fatty acids, squalene (used in cosmetics and vaccines), exopolysaccharides (used in pharmaceuticals), enzymes, aquaculture feed, pigments and lipids suitable for biodiesel composition.”

The authors say the integration of bioprocessing, fermentation and advanced manufacturing result in economically sustainable processes that would enable industrial-scale production of these biologically important products, including the development of plant-based meats.

“To produce plant-based meats, it requires proteins, nutrients and fats. Thraustochytrids are an oleaginous (oily) microorganism that produce high lipid (fat) content and it is expected that these fats will mimic the structure of animal fats, enhancing the sensory properties of plant-based meats and confer a delicious taste,” said Puri.

“With the growth in popularity of vegan and vegetarian diets, alongside concerns about the sustainability of our agricultural industries and its impact on fossil fuel emissions, we can see that finding alternatives to animal products is a major growing market.”

This month, Puri and his team signed a partner agreement with Nourish Ingredients to further develop animal-free meat products.

The project – Advanced lipid fermentation facility of local manufacture of future foods – has received $2.829 million via the federal government’s Cooperative Research Centres projects grants, which support short-term multi-institutional collaborative research projects.

“We are looking to develop an algal production system that can provide a predictable and environmentally friendly alternative to animal sources and can serve growing vegetarian markets in Australia,” said Puri.

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